BIAFINE in the three stages of healing
Stage 1 : Inflammation phase
- Oil in water emulsion extracts exudate for drainage
via osmotic and capilliary action : resulting hyperosmotic emulsion absorbs debris, necrotic tissue, bacteria and etc.
- A mildly alkaline ( ph 6.8-7.6 ), tensio active soft soap which assist in cleansing.
- An occlusive dressing which provides the optimum environment for healing, inhibits the loss of water, and protects from bacterial contamination.
- Local vasolidation, withthe opening of precapillary sphincters, results in a " pro-inflammatory " response and the delivery of essential wound repairing nutrients/ cells.
Stage 2 : Proliferation phase
- Massive recruitment of macrophages remove bacteria/ contaminants known to inhibit healing.
- A significant decrease in IL-6 levels causes reduced feedback control of IL-1, stimulating fibroblasts and secretion of collagen/ collagenase, therefore promoting rapid tissue remodelling.
Stage 3 : Maturation phase
- Effect on cytokine ( IL-1/ IL-6) concentrations stimulate formation of ordered collagen beds; the platform for rapid and quality-structured epithelial growth.
- Emollient action reduces the extent of retraction at the site, epithelial growth is promoted.
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